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Discovery of Orally Bioavailable Phthalazinone Analogues as an ENPP1 Inhibitor for STING-Mediated Cancer Immunotherapy

Cho, Y.; Kang, M.; Ji, S. H.; Jeong, H. J.; Jung, J. E.; Oh, D. H.; Park, S.; Park, Y.-Y.; Choi, J.; Kim, S.; Kim, N.-J.; Lee, D.-H; Park, C. S.*; Han, S.-J.*; Lee, S.*; Choi, J.*

J. Med. Chem. 2023, ASAP. DOI:10.1021/acs.jmedchem.3c01061 




N4-phenylquinazoline-4,6-diamine as a tunable fluorescent scaffold for the development of fluorescent probes.

Lee, J.; Choi, S.-K.; Aslama, Lim, W. Lee, J.; Ko, J.; Ryu, C. H.; Lee, K. M.; Jung, Y. M.; Yoo, H. S.; Park, J. H.; Lee, S.; Choi, J.; Kim, E.*; Park, J.*

Dyes Pigm. 2023, 210, 110987. DOI: 10.1016/j.dyepig.2022.110987

Effect of the Duration of NSAID Use on COVID-19.

Kim, K.; Yoon, S.; Choi, J.; Lee, S.*

Medicina 2022, 58, 1713. DOI: 10.3390/medicina58121713

Small molecule ectonucleotide pyrophosphatase/phosphodiesterase 1 inhibitors in cancer immunotherapy for harnessing innate immunity.

Choi, J.*

Bull. Korean Chem. Soc. 2023, 44, 88–99. DOI:


Finite element analyses of lateral condyle fracture fixation in paediatrics regarding configuration of Kirschner-wire.

Jeon, S.; Ahn, W.; Oh, J.; Chung, J.; Choi, J.; Lee, S.*

BMC Musculoskeletal Disord. 2022, 23, 940. DOI: 10.1186/s12891-022-05897-3

The Association of Low Skeletal Muscle Mass with Complex Distal Radius Fracture.

Oh, C.-H.; Kim, J.; Kim, J.; Yoon, S.; Jung, Y.; Lee, H. I.; Choi, J.; Lee, S.*; Han, S.-H.*

J. Clin. Med. 2022, 11, 5581. DOI:

miR-31-3p functions as a tumor suppressor by directly targeting GABBR2 in prostate cancer.

Choi, S.†; Lee, S.†; Han, Y.-H.; Choi, J.; Kim, I.; Lee, J.; An, H.-J.* († contributed equally)

Front. Oncol. 2022, 12, 945057. DOI:

Colchicine as a novel drug for the treatment of osteosarcoma through drug repositioning based on an FDA drug library.

Park, K.-C.; Kim, K. S.; Jung, B. S.; Yoon, S.; Ahn, W.; Jeong, S.; Choi, J.; Lee, S.*

Front. Oncol. 2022, 12, 893951. DOI:

Hair methylmercury levels are inversely correlated with arterial stiffness.

Park, K.-C.; Kim, K. S.; Jung, B. S.; Yoon, S.; Ahn, W.; Jeong, S.; Choi, J.; Lee, S.*

Atherosclerosis 2022, 357, 14–19. DOI: 10.1016/j.atherosclerosis.2022.08.003

Synthesis of Benzoxaphosphole 1-Oxide Heterocycles via a Three-Component Coupling Reaction Involving Arynes, Phosphites, and Ketones

Jeong, H. J.; Kim, J. H.; Lee, J. K.; Yoon, H. J.; Choi, J.*; Han, S.-J.* († contributed equally)

Org. Lett. 202224, 2192−2196DOI: 10.1021/acs.orglett.2c00515

Harnessing aggregation-induced emission property of indolizine derivative as a fluorogenic bioprobe for endoplasmic reticulum.

Arun, V.; Choi, S.-K.; Han, J. H.; Choi, H.; Kim, H.-M.; Kim, W.; Choi, J.*; Kim, J.*; Kim, E.*

Dyes Pigm. 2022, 200, 110118. DOI: 10.1016/j.dyepig.2022.110118


Fluorescent sensor array for high-precision pH classification with machine learning-supported mobile devices.

Kim, H.; Lee, S.; Min, J. S.; Kim, E.; Choi, J.; Ko, J. G.*; Kim, E.*

Dyes Pigm. 2021, 193, 109492. DOI: 10.1016/j.dyepig.2021.109492

Benefits of Chemical Sugar Modifications Introduced by Click Chemistry for Glycoproteomic Analyses.

Calle, B.; Bineva-Todd, G.; Marchesi, A.; Flynn, H.; Ghirardello, M; Tastan, O. Y.; Roustan, C.; Choi, J.; Galan, M. C.; Schumann, B.*; Malaker, S. A.*

J. Am. Soc. Mass Spectrom. 2021, 32, 23662375. DOI:10.1021/jasms.1c00084

Optimization of Metabolic Oligosaccharide Engineering with Ac4GalNAlk and Ac4GlcNAlk by an Engineered Pyrophosphorylase.

Cioce, A; Bineva-Todd, G.; Agbay, A. J.; Choi, J.; Wood, T. M.; Debets, M. F.; Browne, W. M.; Douglas, H. L.; Roustan, C.; Tastan, O. Y.; Kjaer, S.; Bush, J. T.; Bertozzi, C. R.; Schumann, B.*

ACS Chem. Biol. 2021, 16, 10, 1961–1967. DOI:10.1021/acschembio.1c00034

Metabolic precision labeling enables selective probing of O-linked N-acetylgalactosamine glycosylation.

Debets, M. F.; Tastan, O. Y.; Wisnovsky, S. P.; Malaker, S. A.; Angelis, N.; Moeckl, L. K. R.; Choi, J.; Flynn, H.; Wagner, L. J. S.; Bineva-Todd, G.; Antonopoulos, A.; Cioce, A.; Browne, W. M.; Li, Z.; Briggs, D. C.; Douglas, H. L.; Hess, G. T.; Agbay, A. J.; Roustan, C.; Kjaer, S.; Haslam, S. M.; Snijders, A. P.; Bassik, M. C.; Moerner, W. E.; Li, V. S. W.; Bertozzi, C. R.; Schumann, B.*

Proc. Natl. Acad. Sci. U. S. A. 2020, 117, 2529325301. DOI: 10.1073/pnas.2007297117

Bump-and-Hole Engineering Identifies Specific Substrates of Glycosyltransferases in Living Cells.

Schumann, B.*; Malaker, S. A.; Wisnovsky, S. P.; Debets, M. F.; Agbay, A. J.; Fernandez, D.; Wagner, L. J. S.; Lin, L.; Li, Z.; Choi, J.; Fox, D. M.; Peh, J.; Gray, M. A.; Pedram, K.; Kohler, J. J.; Mrksich, M.; Bertozzi C. R.* 

Mol. Cell 202078, 824−883.  DOI: 10.1016/j.molcel.2020.03.030

Phase Behavior of Disk Coil Block Copolymers under Cylindrical Confinement: Curvature Induced Structural Frustrations.

Ha, M. Y.†; Ryu, J. H.†; Cho, E. N.; Choi, J.; Kim, Y.*; Lee, W. B.* († contributed equally)

Phys. Rev. E 2019, 100, 052502.  DOI: 10.1103/PhysRevE.100.052502

Engineering Orthogonal Polypeptide GalNAc-Transferase and UDP-Sugar Pairs.

Choi, J.†; Wagner, L. J. S.†; Timmermans, S. B. P. E.; Malaker, S. A.; Schumann, B.; Gray, M. A.; Debets, M. F.; Takashima, M.;Gehring, J.; Bertozzi, C. R.* († contributed equally)

J. Am. Chem. Soc. 2019, 141, 13442−13453.  DOI: 10.1021/jacs.9b04695


Theoretical Study on the Toxicity of ‘Novichok’ Agent Candidates.

Jeong, K.*; Choi, J.

R. Soc. Open Sci. 2019, 6, 190414.  DOI: 10.1098/rsos.190414

Transition Metal-Catalyzed Alkyl–Alkyl Bond Formation: Another Dimension in Cross-Coupling Chemistry.

Choi, J.; Fu, G. C.*     

Science 2017, 356, eaaf7230.  DOI: 10.1126/science.aaf7230

A General, Modular Method for the Catalytic Asymmetric Synthesis of Alkylboronate Esters.

Schmidt, J.; Choi, J.; Liu, A. T.; Slusarczyk, M.; Fu, G. C.*

Science 2016, 354, 1265−1269.  DOI: 10.1126/science.aai8611

Enantioselective Decarboxylative Arylation of α-Amino Acids via the Merger of Photoredox and Nickel Catalysis.

Zuo, Z.†; Cong, H.†; Li, W; Choi, J.; Fu, G. C.*; MacMillan, D. W. C.* († contributed equally)

J. Am. Chem. Soc. 2016, 138, 1832−1835.  DOI: 10.1021/jacs.5b13211

Stereoconvergent Arylations and Alkenylations of Unactivated Alkyl Electrophiles: The Catalytic

Enantioselective Synthesis of Secondary Sulfonamides and Sulfones.

Choi, J.; Martín-Gago, P.; Fu, G. C.*

J. Am. Chem. Soc. 2014, 136, 12161−12165 (spotlighted in JACS).  DOI: 10.1021/ja506885s

A Versatile Approach to Ullmann C−N Couplings at RoomTemperature: New Families of Nucleophiles and

Electrophiles for Photoinduced, Copper-Catalyzed Processes.

Ziegler, D. T.; Choi, J.; Muñoz-Molina, J. M.; Bissember, A. C.; Peters, J. C.*; Fu, G. C.*

J. Am. Chem. Soc. 2013, 135, 13107−13112.  DOI: 10.1021/ja4060806

Catalytic Asymmetric Synthesis of Secondary Nitriles via Stereoconvergent Negishi Arylations and 

Alkenylations of Racemic α-Bromonitriles.

Choi, J.; Fu, G. C.*

J. Am. Chem. Soc. 2012, 134, 9102−9105.  DOI: 10.1021/ja303442q


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